Interest I: Protein Folding
Protein folds to functional structure according to its amino acid sequence (Fig. 1A). We are interested in how this folding/assembly...
Interest II: Protein-ligand Interaction
Understanding the protein-drug or protein-metabolite interactions (Fig. 2A) is invaluable in medical and biological applications. Our lab...
Interest III: Protein Engineering
Protein (Enzyme) activity and stability are critical in its practical applications. We are engineering proteins with controllable...
Ongoing Project I:
Uridine Phosphorylase is an important enzyme in metabolism (Fig. 4A). We are studying the effect of a common metabolite, ATP, on the...
Ongoing Project II:
IgG binding domain of protein A from Staphylococcus aureus has rapid unfolding/folding kinetics (RUF). We are engineering fusion proteins...
On Going Project III
Coming Soon.........